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KMID : 1161420230260100705
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Journal of Medicinal Food
2023 Volume.26 No. 10 p.705 ~ p.720
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Controlling Intestinal Infections and Digestive Disorders Using Probiotics
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Richard Migisha
Md Faruque Ahmad
Lilian Bulage
Rubina Roy
Rudrarup Bhattacharjee
Eman Shama
Indira Gahatraj
Manisha Sehrawat
Vaishali Dasriya
Harmeet Singh Dhillon
Monica Puniya
Mrinal Samtiya
Tejpal Dhewa
Rotimi E. Aluko
Gulab D. Khedkar
Antonio Raposo
Marwan Shinawi
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Abstract
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After consumption, probiotics provide health benefits to the host. Probiotics and their metabolites have therapeutic and nutritional properties that help to alleviate gastrointestinal, neurological, and cardiovascular problems. Probiotics strengthen host immunity through various mechanisms, including improved gut barrier function, receptor site blocking, competitive exclusion of pathogens, and the production of bioactive molecules. Emerging evidence suggests that intestinal bowel diseases can be fatal, but regular probiotic consumption can alleviate disease symptoms. The use and detailed description of the health benefits of probiotics to consumers in terms of reducing intestinal infection, inflammation, and digestive disorders are discussed in this review. The well-designed and controlled studies that examined the use of probiotics to reduce life-threatening activities caused by intestinal bowel diseases are also covered. This review discussed the active principles and potency of probiotics as evidenced by the known effects on host health, in addition to providing information on the mechanism of action.
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KEYWORD
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digestive disorders, gut barrier function, Helicobacter pylori, immunomodulation, nutritional attributes, probiotics
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